Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 7/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049782 | 0.91 | PTGIR (0.38) | PTGIRTRPM8PARP1PARP2KDM4C | |
| SCHEMBL9048929 | 0.82 | TDP1 (0.36) | PTGIRTRPM8 | |
| SCHEMBL9568075 | 0.81 | TRPM8 (0.48) | TRPM8PARP1PARP2KDM4CHTR6 | |
| SCHEMBL9048583 | 0.81 | PTGIR (0.45) | PTGIRKDM4C | |
| SCHEMBL9048510 | 0.80 | PTGIR (0.36) | PTGIRTRPM8PARP1PARP2KDM4C | |
| SCHEMBL9046447 | 0.77 | KDM4C (0.39) | PTGIRTRPM8KDM4C | |
| SCHEMBL9050469 | 0.77 | KMT2A (0.36) | PTGIRTRPM8 | |
| SCHEMBL9046594 | 0.76 | PTGIR (0.36) | PTGIRTRPM8PARP1PARP2KDM4C | |
| SCHEMBL9050656 | 0.76 | KDM4E (0.40) | PTGIRCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9050611 | 0.75 | KMT2A (0.44) | PTGIRKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |