Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568032 | 0.89 | TRPM8 (0.47) | TRPM8PARP1PARP2MTNR1BKDM4C | |
| SCHEMBL5444606 | 0.85 | TRPM8 (0.45) | TRPM8PARP1PARP2KDM4CKDM5A | |
| SCHEMBL9048581 | 0.81 | PTGIR (0.39) | TRPM8PARP1PARP2KDM4CHTR6 | |
| SCHEMBL9567968 | 0.79 | TRPM8 (0.49) | TRPM8MTNR1BHTTALDH1A1 | |
| SCHEMBL9048583 | 0.78 | PTGIR (0.45) | KDM4C | |
| SCHEMBL9567976 | 0.76 | TRPM8 (0.47) | TRPM8PARP1PARP2KDM4CKDM5A | |
| SCHEMBL4077454 | 0.74 | USP2 (0.47) | KDM4CKDM5AKDM5BTSHRHTT | |
| SCHEMBL1725811 | 0.74 | BLM (0.50) | PARP1PARP2KDM4CKDM5AKDM5B | |
| SCHEMBL30572310 | 0.74 | BLM (0.50) | PARP1PARP2KDM4CKDM5AKDM5B | |
| SCHEMBL9567971 | 0.73 | PRMT5 (0.53) | MTNR1BKDM4CKDM5AKDM5BPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |