Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PTGIR | P43119 | 4/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568022 | 0.84 | ALDH1A1 (0.52) | KDM4EALDH1A1MEN1KMT2AEPHX1 | |
| SCHEMBL9050659 | 0.83 | PTGIR (0.40) | KDM4EALDH1A1MEN1KMT2APTGIR | |
| SCHEMBL9046447 | 0.83 | KDM4C (0.39) | PTGIR | |
| SCHEMBL9048510 | 0.79 | PTGIR (0.36) | PTGIREPHX1 | |
| SCHEMBL9048581 | 0.76 | PTGIR (0.39) | PTGIRCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9049782 | 0.75 | PTGIR (0.38) | KMT2APTGIRCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9050611 | 0.71 | KMT2A (0.44) | KDM4EALDH1A1MEN1KMT2APTGIR | |
| SCHEMBL9046594 | 0.70 | PTGIR (0.36) | PTGIRNPSR1 | |
| SCHEMBL9048344 | 0.70 | PTGIR (0.45) | ALDH1A1MEN1KMT2APTGIRNPSR1 | |
| SCHEMBL9048207 | 0.69 | PTGIR (0.46) | KDM4EALDH1A1MEN1KMT2APTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |