Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | FCER2 | P06734 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048596 | 0.80 | PTGIR (0.43) | MTNR1AMTNR1BCA1CA2 | |
| SCHEMBL9568027 | 0.79 | TRPM8 (0.46) | TRPM8HSD11B1 | |
| SCHEMBL9568019 | 0.76 | MMP1 (0.44) | TRPM8AKR1C3MMP1FCER2MMP9 | |
| SCHEMBL9568023 | 0.74 | TRPM8 (0.48) | TRPM8HSD11B1 | |
| SCHEMBL2597095 | 0.73 | MTNR1A (0.46) | PLAUMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL3611898 | 0.71 | PLAU (0.46) | AKR1C3PLAUMTNR1AMTNR1BCA1 | |
| SCHEMBL27129419 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL26984334 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL9568005 | 0.69 | TRPM8 (0.39) | TRPM8PLAUMTNR1AMTNR1BANPEP | |
| SCHEMBL11472821 | 0.69 | MTNR1A (0.45) | AKR1C3PLAUMTNR1AMTNR1BCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |