Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | PTGIR | P43119 | 11/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047215 | 0.89 | TBXAS1 (0.57) | TBXAS1PTGIRPTGDR | |
| SCHEMBL9427288 | 0.84 | TBXAS1 (0.40) | TBXAS1PTGIRTRPM8LMNANR1I2 | |
| SCHEMBL9048005 | 0.83 | TBXAS1 (0.37) | TBXAS1TRPM8NR1I2 | |
| SCHEMBL9568045 | 0.83 | TAOK1 (0.39) | TBXAS1TRPM8LMNASLC6A2SLC6A4 | |
| SCHEMBL9427236 | 0.79 | PTGIR (0.43) | PTGIR | |
| SCHEMBL9048119 | 0.78 | PTGIR (0.42) | PTGIR | |
| SCHEMBL9427442 | 0.78 | PTGIR (0.41) | PTGIR | |
| SCHEMBL9049522 | 0.77 | TBXAS1 (0.41) | TBXAS1PTGIRPTGDR | |
| SCHEMBL9051195 | 0.76 | TBXAS1 (0.44) | TBXAS1PTGIR | |
| SCHEMBL9048596 | 0.73 | PTGIR (0.43) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |