Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 18/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046372 | 0.91 | PTGIR (0.45) | PTGIRCA1CA2ACHETBXAS1 | |
| SCHEMBL8858458 | 0.88 | PTGIR (0.58) | PTGIRTBXAS1PTGDR | |
| SCHEMBL9048138 | 0.84 | PTGIR (0.52) | PTGIRTBXAS1 | |
| SCHEMBL9048870 | 0.83 | ALDH1A1 (0.40) | PTGIR | |
| SCHEMBL9049235 | 0.81 | PTGIR (0.44) | PTGIRCA1CA2ACHETBXAS1 | |
| SCHEMBL8858396 | 0.79 | PTGIR (0.61) | PTGIRTBXAS1PTGDR | |
| SCHEMBL9047459 | 0.79 | PTGIR (0.44) | PTGIRCA1CA2ACHEPTGDR | |
| SCHEMBL8858398 | 0.78 | PTGIR (0.59) | PTGIRTBXAS1 | |
| SCHEMBL9045875 | 0.78 | LMNA (0.47) | PTGIRCA1CA2ACHE | |
| SCHEMBL9045695 | 0.76 | MTNR1A (0.44) | PTGIRCA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |