Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 11/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048637 | 0.85 | PTGIR (0.45) | PTGIREPHX2CA1CA2ACHE | |
| SCHEMBL9045885 | 0.85 | PTGIR (0.58) | LMNAPTGIR | |
| SCHEMBL9048138 | 0.83 | PTGIR (0.52) | PTGIRALDH1A1 | |
| SCHEMBL9048873 | 0.78 | PTGIR (0.42) | PTGIRCA1CA2ACHE | |
| SCHEMBL9045869 | 0.78 | LMNA (0.51) | LMNAEPHX2ALDH1A1KMT2A | |
| SCHEMBL9567957 | 0.78 | LMNA (0.63) | LMNAALDH1A1MTNR1AMTNR1BKMT2A | |
| SCHEMBL9427064 | 0.77 | LMNA (0.45) | LMNAPTGIR | |
| SCHEMBL9046372 | 0.77 | PTGIR (0.45) | PTGIRCA1CA2ACHE | |
| SCHEMBL9048371 | 0.76 | PTGIR (0.50) | PTGIR | |
| SCHEMBL9051610 | 0.74 | SLC6A4 (0.40) | LMNAPTGIRACHEALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |