Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050191 | 0.71 | PARP1 (0.31) | PARP1 | |
| SCHEMBL7484709 | 0.65 | PARP1 (0.39) | PARP1 | |
| SCHEMBL8551730 | 0.64 | NOS1 (0.34) | PARP1 | |
| SCHEMBL8549330 | 0.63 | L3MBTL4 (0.45) | PARP1 | |
| SCHEMBL9050184 | 0.62 | PARP1 (0.39) | PARP1 | |
| SCHEMBL8550551 | 0.62 | HTR1B (0.41) | — | |
| SCHEMBL1976575 | 0.62 | PARP1 (0.46) | PARP1 | |
| SCHEMBL15427984 | 0.62 | CYP3A4 (0.39) | PARP1 | |
| SCHEMBL8118010 | 0.62 | GAA (0.39) | PARP1 | |
| SCHEMBL8550081 | 0.60 | PARP1 (0.43) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736025-A1 | DYHYDROBENZOFURANYL-BIPHENYL CARBOXAMIDES HAVING 5HT 1D? ANTAGONISTIC ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017401-A1 | DYHYDROBENZOFURANYL-BIPHENYL CARBOXAMIDES HAVING 5HT1D ANTAGONISTIC ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-06-29 | — | — | WO | disclosed |