Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278784 | 0.81 | HIF1A (0.48) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL3656311 | 0.81 | SMN1; SMN2 (0.48) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL27799072 | 0.79 | TRPA1 (0.50) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL1547275 | 0.77 | HIF1A (0.44) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL7619909 | 0.77 | SLC6A2 (0.48) | SMN1; SMN2HIF1ASLC6A2TAAR1LMNA | |
| SCHEMBL9049025 | 0.75 | TRPA1 (0.51) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL476211 | 0.75 | PPARG (0.46) | SMN1; SMN2HIF1ASLC6A2TAAR1LMNA | |
| SCHEMBL357502 | 0.75 | SMN1; SMN2 (0.40) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL2641207 | 0.74 | PPARG (0.44) | SMN1; SMN2HIF1ASLC6A2TAAR1LMNA | |
| SCHEMBL27768873 | 0.74 | SMN1; SMN2 (0.48) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385456-B1 | High surface hardness transparent resin and polymerizable monomer | MITSUI TOATSU CHEMICALS (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5084538-A | HIGH SURFACE HARDNESS TRANSPARENT RESIN PREPARED FROM A COMPOUND HAVING AT LEAST ONE ISOPROPENYL PHENYL GROUP | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-01-28 | — | — | US | disclosed |