Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 4/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050089 | 0.85 | DRD3 (0.60) | ADRA1BADRA1DADRA1AHTR7HTR1A | |
| SCHEMBL9047511 | 0.83 | HTR1A (0.54) | ADRA1BADRA1DADRA1AHTR7HTR1A | |
| SCHEMBL9049140 | 0.80 | HTR1A (0.56) | ADRA1BADRA1DADRA1AHTR7HTR1A | |
| SCHEMBL9047811 | 0.79 | DRD3 (0.68) | ADRA1BADRA1DADRA1AHTR7HTR1A | |
| SCHEMBL9049703 | 0.79 | DRD3 (0.69) | ADRA1BADRA1DADRA1AHTR7HTR1A | |
| SCHEMBL9050587 | 0.79 | DRD3 (0.56) | ADRA1BADRA1DADRA1AHTR7HTR1A | |
| SCHEMBL9048565 | 0.77 | KCNH2 (0.53) | HTR7HTR1A | |
| SCHEMBL9050903 | 0.77 | DRD3 (0.52) | ADRA1BADRA1DADRA1AHTR7HTR1A | |
| SCHEMBL9049049 | 0.76 | HTR1A (0.61) | HTR7HTR1A | |
| SCHEMBL9048535 | 0.76 | HTR1A (0.65) | HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527081-B1 | Substituted 3-piperazinylalkyl-2,3-dihydro-4H-1,3-benzoxazine-4-ones, their preparation and their therapeutical use | PF MEDICAMENT (FR) | 1996-01-03 | — | — | EP | claimed |
| US-5308844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT, ANALGESIC, HYPOTENSIVE AGENT | PIERRE FABRE MEDICAMENT (FR) | 1994-05-03 | — | — | US | disclosed |