Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568093 | 0.90 | ALDH1A1 (0.45) | ALDH1A1SIGMAR1SLC6A9SLC6A5TSHR | |
| SCHEMBL9049336 | 0.85 | PTGIR (0.39) | ALDH1A1MAPTSLC6A9SLC6A5TSHR | |
| SCHEMBL8858542 | 0.82 | PTGIR (0.58) | SIGMAR1MAPTTSHRTDP1PTGIR | |
| SCHEMBL9567974 | 0.78 | ALDH1A1 (0.34) | ALDH1A1SIGMAR1SLC6A9SLC6A5TSHR | |
| SCHEMBL9049399 | 0.74 | KMT2A (0.41) | ALDH1A1MAPTSLC6A9SLC6A5TSHR | |
| SCHEMBL7825602 | 0.72 | SIGMAR1 (0.49) | ALDH1A1SIGMAR1TSHRRAB9A | |
| SCHEMBL8858403 | 0.71 | PTGIR (0.61) | SIGMAR1MAPTSLC6A9SLC6A5TSHR | |
| SCHEMBL9049403 | 0.71 | PTGIR (0.45) | ALDH1A1SIGMAR1SLC6A9SLC6A5TSHR | |
| SCHEMBL20825056 | 0.68 | SIGMAR1 (0.45) | ALDH1A1SIGMAR1RAB9AHPGD | |
| SCHEMBL28294223 | 0.68 | SIGMAR1 (0.45) | ALDH1A1SIGMAR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |