Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 12/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047414 | 0.80 | LMNA (0.47) | LMNAGAAMAPTHTTSMN1; SMN2 | |
| SCHEMBL9050224 | 0.77 | LMNA (0.42) | LMNAGAAMAPTHTTSMN1; SMN2 | |
| SCHEMBL9057868 | 0.76 | KMT2A (0.49) | LMNACCR2 | |
| SCHEMBL9050331 | 0.74 | PTGDR2 (0.42) | CCR2 | |
| SCHEMBL9049502 | 0.74 | MAPT (0.43) | LMNAGAAMAPTHTTSMN1; SMN2 | |
| SCHEMBL11266983 | 0.74 | CCR2 (0.53) | LMNAGAAMAPTHTTSMN1; SMN2 | |
| SCHEMBL11260693 | 0.72 | APEX1 (0.62) | LMNAGAAMAPTHTTSMN1; SMN2 | |
| SCHEMBL13811595 | 0.70 | MEN1 (0.51) | MAPTHTTSMN1; SMN2 | |
| SCHEMBL9049601 | 0.68 | LMNA (0.49) | LMNAGAAMAPTHTTSMN1; SMN2 | |
| SCHEMBL10487872 | 0.67 | CCR2 (0.60) | LMNAMAPTCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456835-B1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5234928-A | Inhibit platelet aggregation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0456835-A1 | QUINAZOLINE-3-ALKANOIC ACID DERIVATIVE, SALT THEREOF, AND PRODUCTION THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |