Gamma-Aminobutyric Acid

Gamma-Aminobutyric Acid

SCHEMBL9049554

NCCCC(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.71
BLM P54132 3/20 0.71
THRB P10828 2/20 0.71
KMT2A Q03164 2/20 0.71
NPSR1 Q6W5P4 2/20 0.71
TSHR P16473 2/20 0.71
HDAC6 Q9UBN7 2/20 0.71
GABRR3 A8MPY1 1/20 0.71
GABRP O00591 1/20 0.71
GABRD O14764 1/20 0.71
HDAC3 O15379 1/20 0.71
GABBR2 O75899 1/20 0.71
CYP1A2 P05177 1/20 0.71
GABRA1 P14867 1/20 0.71
GABRB1 P18505 1/20 0.71
GABRG2 P18507 1/20 0.71
GABRR1 P24046 1/20 0.71
GABRB3 P28472 1/20 0.71
GABRR2 P28476 1/20 0.71
SLC6A1 P30531 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
5-Aminovaleric Acid SCHEMBL28804498 0.93 NFKB1 (0.73) LMNABLMTHRBKMT2ANPSR1
Trifluoroacetic Acid SCHEMBL6490884 0.86 LMNA (0.50) LMNABLMTHRBKMT2ANPSR1
Trifluoroacetic Acid SCHEMBL8201988 0.85 LMNA (0.48) LMNABLMTHRBKMT2ANPSR1
Glutarate SCHEMBL4768243 0.85 SLC22A6 (0.65) LMNABLMTHRBKMT2ANPSR1
Trifluoroacetic Acid SCHEMBL6490887 0.85 HRH4 (0.50) LMNABLMTHRBKMT2ANPSR1
Trifluoroacetic Acid SCHEMBL3149196 0.85 ODC1 (0.48) LMNABLMTHRBKMT2ANPSR1
Trifluoroacetic Acid SCHEMBL10619767 0.85 ODC1 (0.48) LMNABLMTHRBKMT2ANPSR1
Gamma-Aminobutyric Acid SCHEMBL3973563 0.84 LMNA (1.00) LMNABLMTHRBKMT2ANPSR1
Gamma-Aminobutyric Acid SCHEMBL4878 0.84
Gamma-Aminobutyric Acid SCHEMBL190459 0.84 LMNA (1.00) LMNABLMTHRBKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119100941-A Preparation and application of contracture medicine with synergistic antidepressant effect and composition thereof 江苏海洋大学 2024-12-10 CN disclosed
EP-0715623-A1 PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1996-06-12 EP disclosed