Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL29896408 | 0.88 | LMNA (0.60) | SLC22A6LMNATSHRNFKB1PMP22 | |
| Succinic Acid SCHEMBL29896406 | 0.88 | LMNA (0.60) | SLC22A6LMNATSHRNFKB1PMP22 | |
| Gamma-Aminobutyric Acid SCHEMBL9049554 | 0.85 | LMNA (0.71) | SLC22A6LMNATSHRNFKB1PMP22 | |
| Valeric Acid SCHEMBL27502000 | 0.85 | AKR1B1 (0.61) | SLC22A6TSHRHDAC11KMT2AGPR84 | |
| SCHEMBL23896902 | 0.83 | SLC22A6 (0.58) | SLC22A6LMNATSHRNFKB1PMP22 | |
| 5-Aminovaleric Acid SCHEMBL28804498 | 0.83 | NFKB1 (0.73) | SLC22A6LMNATSHRNFKB1PMP22 | |
| Nonanoate SCHEMBL23043748 | 0.81 | GPR84 (0.74) | SLC22A6TSHRHDAC11CYP1A2KMT2A | |
| Nonanoate SCHEMBL23043798 | 0.81 | GPR84 (0.74) | SLC22A6TSHRHDAC11CYP1A2KMT2A | |
| Glutarate SCHEMBL6701735 | 0.80 | — | — | |
| Glutarate SCHEMBL7414 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858159-A | Chemical compounds | GLAXOSMITHKLINE LLC | 2013-01-02 | — | — | CN | disclosed |
| EP-1648873-A4 | NEUROPROTECTIVE MACROCYLIC COMPOUNDS AND METHODS FOR THEIR USE | NEUREN PHARMACEUTICALS LTD (NZ) | 2008-06-25 | — | — | EP | disclosed |
| EP-1648873-A2 | NEUROPROTECTIVE MACROCYLIC COMPOUNDS AND METHODS FOR THEIR USE | Neuronz Limited (NZ) | 2006-04-26 | — | — | EP | disclosed |
| WO-2004084809-A2 | NEUROPROTECTIVE MACROCYLIC COMPOUNDS AND METHODS FOR THEIR USE | NEUREN PHARMACEUTICALS LTD. (NZ) | 2004-10-07 | — | — | WO | disclosed |