Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355050 | 0.80 | P2RX7 (0.48) | ALDH1A1YTHDC1NPC1HPGDRAB9A | |
| SCHEMBL29601580 | 0.80 | P2RX7 (0.48) | ALDH1A1YTHDC1NPC1HPGDRAB9A | |
| SCHEMBL30586405 | 0.77 | PDE8A (0.39) | ALDH1A1YTHDC1NPC1HPGDRAB9A | |
| SCHEMBL30586367 | 0.77 | YTHDC1 (0.38) | CDK1ALDH1A1YTHDC1NPC1HPGD | |
| SCHEMBL3441002 | 0.77 | CDK1 (0.54) | CDK1 | |
| SCHEMBL16105004 | 0.74 | ALDH1A1 (0.54) | CDK1ALDH1A1L3MBTL1NPC1HPGD | |
| SCHEMBL7939007 | 0.70 | ALDH1A1 (0.51) | CDK1ALDH1A1L3MBTL1NPC1HPGD | |
| SCHEMBL5999067 | 0.69 | ALDH1A1 (0.40) | ALDH1A1YTHDC1NPC1HPGDRAB9A | |
| SCHEMBL2054791 | 0.69 | HSP90AB1 (0.52) | — | |
| SCHEMBL8348688 | 0.69 | HDAC1 (0.64) | CDK1YTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673376-B1 | BICYCLIC PYRIMIDINE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | ADIR (FR) | 1996-05-22 | — | — | EP | disclosed |
| US-5508277-A | Bicyclic pyrimidines | ADIR ET COMPAGNIE (FR) | 1996-04-16 | — | — | US | disclosed |
| EP-0673376-A1 | NOVEL BICYCLIC PYRIMIDINE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS. | ADIR (FR) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013668-A1 | NOVEL BICYCLIC PYRIMIDINE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | ADIR ET COMPAGNIE (FR) | 1994-06-23 | — | — | WO | disclosed |