Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.48 |
| ▸ | YTHDC1 | Q96MU7 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDE8A | O60658 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355050 | 1.00 | P2RX7 (0.48) | P2RX7YTHDC1NPC1HPGDRAB9A | |
| SCHEMBL2054791 | 0.84 | HSP90AB1 (0.52) | HDAC4HDAC1HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL5999067 | 0.84 | ALDH1A1 (0.40) | P2RX7YTHDC1NPC1HPGDRAB9A | |
| SCHEMBL30586405 | 0.84 | PDE8A (0.39) | P2RX7YTHDC1NPC1HPGDRAB9A | |
| SCHEMBL30586367 | 0.84 | YTHDC1 (0.38) | P2RX7YTHDC1NPC1HPGDRAB9A | |
| SCHEMBL3441002 | 0.84 | CDK1 (0.54) | PDE8A | |
| SCHEMBL3416144 | 0.81 | P2RX7 (0.46) | P2RX7YTHDC1LMNATP53PDE8A | |
| SCHEMBL9049572 | 0.80 | CDK1 (0.50) | YTHDC1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6288387 | 0.79 | NPC1 (0.52) | P2RX7NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL29444616 | 0.78 | CDK1 (0.51) | P2RX7YTHDC1LMNATP53HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997089-A1 | CYSTEINE BINDING COMPOSITIONS AND METHODS OF USE THEREOF | University Of Virginia Patent Foundation (US) | 2022-05-18 | — | — | EP | disclosed |