Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050656 | 0.84 | KDM4E (0.40) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL9050659 | 0.82 | PTGIR (0.40) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL9568024 | 0.80 | KDM4C (0.48) | ALDH1A1MEN1KMT2ATRPM8HTR6 | |
| SCHEMBL9568025 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1KMT2APDPK1 | |
| SCHEMBL9567976 | 0.75 | TRPM8 (0.47) | KMT2ATRPM8HTR6PDPK1HTT | |
| SCHEMBL9568075 | 0.72 | TRPM8 (0.48) | ALDH1A1TRPM8HTR6PDPK1HTT | |
| SCHEMBL9568032 | 0.71 | TRPM8 (0.47) | TRPM8HTR6PDPK1PARP1PARP2 | |
| SCHEMBL5444606 | 0.69 | TRPM8 (0.45) | ALDH1A1TRPM8HTR6PDPK1HTT | |
| SCHEMBL1725811 | 0.67 | BLM (0.50) | ALDH1A1HTTPARP1PARP2 | |
| SCHEMBL30572310 | 0.67 | BLM (0.50) | ALDH1A1HTTPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |