Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050973 | 0.71 | ALDH1A1 (0.48) | CA12CA9ALDH1A1HPGDRECQL | |
| SCHEMBL301798 | 0.67 | ALDH1A1 (0.68) | CA12CA9ALDH1A1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL7362553 | 0.66 | ALDH1A1 (0.66) | CA12CA9ALDH1A1TSHRMAPK1 | |
| SCHEMBL634317 | 0.66 | ALDH1A1 (0.66) | CA12CA9ALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL12481388 | 0.66 | ALDH1A1 (0.66) | CA12CA9ALDH1A1TSHRMAPK1 | |
| SCHEMBL28141867 | 0.64 | ALDH1A1 (0.49) | CA12CA9ALDH1A1TSHRHPGD | |
| SCHEMBL652685 | 0.63 | LTA4H (0.47) | ALDH1A1HTTZDHHC2MAPK1LMNA | |
| Formic Acid Phenyl Ester SCHEMBL28329438 | 0.63 | LTA4H (0.48) | ALDH1A1TSHRHTTZDHHC2MAPK1 | |
| SCHEMBL19785139 | 0.63 | CA12 (0.74) | CA12CA9HTTMEN1KMT2A | |
| SCHEMBL9142888 | 0.63 | MEN1 (0.79) | ALDH1A1RECQLHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996035422-A1 | METHODS FOR INHIBITING BONE LOSS | ELI LILLY AND COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |