Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905930 | 0.86 | AR (0.44) | ALDH1A1HPGDRECQLMEN1KMT2A | |
| SCHEMBL634317 | 0.78 | ALDH1A1 (0.66) | ALDH1A1HPGDMEN1KMT2ACA12 | |
| SCHEMBL14873518 | 0.75 | ALOX15 (0.39) | ALDH1A1RECQLMEN1KMT2AHTT | |
| SCHEMBL27767404 | 0.74 | MAOA (0.43) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL728128 | 0.73 | PGR (0.56) | HPGDRECQLMEN1KMT2AHTT | |
| SCHEMBL1604166 | 0.71 | KCNA3 (0.46) | ALDH1A1HPGDRECQLMEN1KMT2A | |
| SCHEMBL9050971 | 0.71 | CA12 (0.42) | ALDH1A1HPGDRECQLMEN1KMT2A | |
| SCHEMBL1674268 | 0.71 | KCNA3 (0.50) | ALDH1A1RECQLKMT2ACA12CA9 | |
| SCHEMBL6782565 | 0.70 | KMT2A (0.45) | ALDH1A1RECQLMEN1KMT2AHTT | |
| SCHEMBL8907383 | 0.70 | MEN1 (0.60) | ALDH1A1HPGDMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996035422-A1 | METHODS FOR INHIBITING BONE LOSS | ELI LILLY AND COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |