Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.58 |
| ▸ | DRD4 | P21917 | 8/20 | 0.58 |
| ▸ | DRD3 | P35462 | 4/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050732 | 0.80 | DRD2 (0.61) | DRD2DRD4DRD3ADRA1AHTR1A | |
| SCHEMBL9052202 | 0.77 | GRIN2B (0.50) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL9050578 | 0.73 | DRD2 (1.00) | DRD2DRD4DRD3ADRA1AHTR1A | |
| SCHEMBL9051399 | 0.73 | DRD2 (0.80) | DRD2DRD4DRD3ADRA1AHTR1A | |
| SCHEMBL318783 | 0.72 | HSD17B3 (0.67) | — | |
| SCHEMBL5193747 | 0.70 | DRD2 (0.57) | DRD2DRD4DRD3ADRA1AHTR1A | |
| SCHEMBL9050720 | 0.69 | DRD2 (0.57) | DRD2DRD4DRD3ADRA1AHTR1A | |
| SCHEMBL9052324 | 0.68 | DRD2 (0.61) | DRD2DRD4DRD3ADRA1AHTR1A | |
| SCHEMBL9053113 | 0.68 | DRD2 (0.56) | DRD2DRD4DRD3ADRA1AHTR1A | |
| SCHEMBL9052696 | 0.68 | DRD2 (0.46) | DRD2DRD4DRD3ADRA1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |