Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 16/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052425 | 0.80 | HPGD (0.47) | GRIN2BHPGDSMN1; SMN2L3MBTL1HTR1A | |
| SCHEMBL9051391 | 0.77 | DRD2 (0.58) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL9052209 | 0.75 | DRD2 (0.64) | GRIN2BDRD2DRD4DRD3HTR1A | |
| SCHEMBL9053117 | 0.73 | DRD2 (0.77) | GRIN2BDRD2DRD4DRD3HTR1A | |
| SCHEMBL9052573 | 0.72 | HPGD (0.46) | HPGDSMN1; SMN2L3MBTL1HTR1A | |
| SCHEMBL8986025 | 0.70 | DRD2 (0.56) | HPGDSMN1; SMN2L3MBTL1DRD2HTR1A | |
| SCHEMBL9053033 | 0.70 | OPRM1 (0.46) | GRIN2BSMN1; SMN2L3MBTL1HTR2A | |
| SCHEMBL9052143 | 0.70 | OPRM1 (0.48) | HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL9050709 | 0.69 | — | — | |
| SCHEMBL8857317 | 0.68 | GRIN2B (0.72) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |