Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.64 |
| ▸ | DRD4 | P21917 | 5/20 | 0.64 |
| ▸ | HTR1A | P08908 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | HRH1 | P35367 | 3/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053117 | 0.92 | DRD2 (0.77) | DRD2DRD4HTR1AHTR2AHRH1 | |
| SCHEMBL9051399 | 0.80 | DRD2 (0.80) | DRD2DRD4HTR1AHTR2AHRH1 | |
| SCHEMBL9052433 | 0.76 | DRD2 (0.68) | DRD2HTR1AHTR2AHRH1GRIN2B | |
| SCHEMBL9052202 | 0.75 | GRIN2B (0.50) | DRD2DRD4HTR1AHTR2AHRH1 | |
| SCHEMBL11615002 | 0.70 | L3MBTL1 (0.50) | DRD2DRD4HTR1AHTR2AHRH1 | |
| SCHEMBL11615000 | 0.70 | L3MBTL1 (0.50) | DRD2DRD4HTR1AHTR2AHRH1 | |
| SCHEMBL9050578 | 0.69 | DRD2 (1.00) | DRD2DRD4HTR1AHTR2AHRH1 | |
| SCHEMBL16600883 | 0.69 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16600881 | 0.69 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL9052603 | 0.69 | DRD2 (0.71) | DRD2DRD4HTR1AHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |