Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050273 | 0.86 | P2RX7 (0.45) | HSD17B10ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9051881 | 0.83 | LMNA (0.46) | TSHRHSD17B10ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL719883 | 0.78 | HSD17B10 (0.63) | TSHRHSD17B10MAPK1NOTUMALDH1A1 | |
| SCHEMBL9052432 | 0.76 | GBA1 (0.42) | TSHRHSD17B10ALDH1A1MEN1GAA | |
| SCHEMBL1802996 | 0.74 | RIPK2 (0.41) | TSHRHSD17B10ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8069989 | 0.73 | ALDH1A1 (0.49) | HSD17B10MAPK1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL719924 | 0.73 | HSD17B10 (0.54) | TSHRHSD17B10MAPK1NOTUMALDH1A1 | |
| SCHEMBL718941 | 0.73 | ALDH1A1 (0.55) | HSD17B10MAPK1NOTUMALDH1A1SMN1; SMN2 | |
| SCHEMBL14312276 | 0.70 | ADORA1 (0.50) | TSHRHSD17B10MAPK1NOTUMALDH1A1 | |
| SCHEMBL718967 | 0.69 | MEN1 (0.53) | TSHRHSD17B10MAPK1NOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034591-A1 | DIAMINOPYRAZOLE-CONTAINING COMPOSITIONS FOR COLOURING KERATIN FIBRES, COLOURING PROCESS, NOVEL DIAMINOPYRAZOLES AND METHOD FOR THEIR PREPARATION | L'OREAL (FR) | 1996-11-07 | — | — | WO | claimed |