Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | HTR1D | P28221 | 3/20 | 0.44 |
| ▸ | HTR1B | P28222 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951102 | 0.80 | HTR1A (0.49) | OPRL1HTR1AHTR1DHTR1BHTR6 | |
| SCHEMBL9054446 | 0.78 | HTR1A (0.47) | OPRL1HTR1AHTR1DHTR1BHTR6 | |
| SCHEMBL7943360 | 0.77 | HRH4 (0.56) | CDK2PRKCZHTR6HRH4 | |
| SCHEMBL7951116 | 0.76 | HRH4 (0.55) | HTR1AHTR1DHTR1BPRKCZHTR6 | |
| SCHEMBL21291588 | 0.75 | KDM4E (0.43) | OPRL1HTR1AHTR1DHTR1BHTR6 | |
| SCHEMBL30516370 | 0.75 | KDM4E (0.43) | OPRL1HTR1AHTR1DHTR1BHTR6 | |
| SCHEMBL7951576 | 0.74 | HRH4 (0.51) | HTR1AHTR6HRH4DRD2DRD3 | |
| SCHEMBL7953632 | 0.74 | HRH4 (0.54) | HTR1AHTR1DHTR1BHTR6HRH4 | |
| SCHEMBL7943312 | 0.74 | HRH4 (0.48) | HRH4 | |
| SCHEMBL6609224 | 0.73 | HTR6 (0.53) | HTR1AHTR1DHTR1BHTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | disclosed |