Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951102 | 0.83 | HTR1A (0.49) | HTR1AHTR1DHTR1BOPRL1DRD2 | |
| SCHEMBL21291588 | 0.78 | KDM4E (0.43) | HTR1AHTR1DHTR1BOPRL1DRD2 | |
| SCHEMBL30516370 | 0.78 | KDM4E (0.43) | HTR1AHTR1DHTR1BOPRL1DRD2 | |
| SCHEMBL9052045 | 0.78 | OPRL1 (0.44) | HTR1AHTR1DHTR1BOPRL1DRD2 | |
| SCHEMBL7943360 | 0.77 | HRH4 (0.56) | HTR6HRH4KDM4EALDH1A1HPGD | |
| SCHEMBL7951116 | 0.76 | HRH4 (0.55) | HTR1AHTR1DHTR1BHTR6HRH4 | |
| SCHEMBL7951576 | 0.74 | HRH4 (0.51) | HTR1ADRD2DRD3HTR6HRH4 | |
| SCHEMBL7953632 | 0.74 | HRH4 (0.54) | HTR1AHTR1DHTR1BDRD2DRD3 | |
| SCHEMBL4675283 | 0.73 | HTR6 (0.76) | HTR1ADRD2DRD3HTR6HTR2A | |
| SCHEMBL4306478 | 0.73 | ADRB1 (0.69) | HTR1ADRD2DRD3HTR6DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | claimed |
| WO-1996041802-A1 | NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-12-27 | — | — | WO | disclosed |