Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316400 | 0.88 | PTGS2 (0.40) | TRPA1L3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL1453904 | 0.79 | L3MBTL1 (0.45) | TRPA1MAOAMAOBL3MBTL1ALDH1A1 | |
| SCHEMBL9602276 | 0.78 | TSHR (0.49) | TRPA1L3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1848023 | 0.78 | ALDH1A1 (0.42) | TRPA1MAOAMAOBL3MBTL1ALDH1A1 | |
| SCHEMBL1721851 | 0.77 | MAOA (0.42) | MAOAMAOBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL20449068 | 0.77 | MAOA (0.47) | MAOAMAOBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL1454786 | 0.77 | MAOA (0.42) | MAOAMAOBL3MBTL1ALDH1A1KDM4E | |
| Fluoride SCHEMBL1335974 | 0.77 | MAOA (0.47) | TRPA1MAOAMAOBL3MBTL1ALDH1A1 | |
| SCHEMBL585722 | 0.77 | MAOA (0.42) | MAOAMAOBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11637842 | 0.77 | FFAR1 (0.45) | L3MBTL1ALDH1A1KDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641207-A4 | ENANTIOMERIC CYNEMICIN ANALOGS, PREPARATION AND USE THEREOF. | SCRIPPS RESEARCH INST (US) | 1996-08-14 | — | — | EP | disclosed |
| US-5527805-A | DNA-CLEAVING, CYTOTOXIC AND ANTI-TUMOR COMPOUNDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0641207-A1 | ENANTIOMERIC CYNEMICIN ANALOGS, PREPARATION AND USE THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5281710-A | Antibiotics or antitumor agents | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-25 | — | — | US | disclosed |
| WO-1993023046-A1 | ENANTIOMERIC CYNEMICIN ANALOGS, PREPARATION AND USE THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-11-25 | — | — | WO | disclosed |