SCHEMBL9052207

SCHEMBL9052207

Cc1cc(SCCCCl)cc(CSc2nc3ccccc3[nH]2)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
MEN1 O00255 2/20 0.53
KDM4E B2RXH2 1/20 0.53
PKM P14618 1/20 0.53
CYP1A2 P05177 2/20 0.52
CYP2E1 P05181 2/20 0.52
CYP2C8 P10632 2/20 0.52
CYP2D6 P10635 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2B6 P20813 2/20 0.52
CYP2C19 P33261 2/20 0.52
LMNA P02545 2/20 0.52
HTT P42858 1/20 0.52
RAB9A P51151 4/20 0.51
NPC1 O15118 3/20 0.51
NOS3 P29474 1/20 0.50
NOS1 P29475 1/20 0.50
NOS2 P35228 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9052566 0.99 KMT2A (0.52) KMT2AALDH1A1MAPTMEN1KDM4E
Hydrochloric Acid SCHEMBL9051788 0.85 LMNA (0.39) KMT2AALDH1A1MAPTMEN1KDM4E
Hydrochloric Acid SCHEMBL9053509 0.84 SMN1; SMN2 (0.52) KMT2AALDH1A1CYP1A2CYP2E1CYP2C8
Hydrochloric Acid SCHEMBL9051713 0.83 OPRL1 (0.39) KMT2AALDH1A1MAPTMEN1KDM4E
SCHEMBL9052994 0.80 MAPT (0.60) KMT2AALDH1A1MAPTMEN1KDM4E
SCHEMBL9053557 0.79 ALDH1A1 (0.51) KMT2AALDH1A1MAPTMEN1KDM4E
Hydrochloric Acid SCHEMBL9052734 0.78 CYP1A2 (0.37) KMT2AMAPTCYP1A2CYP2E1CYP2C8
SCHEMBL9279489 0.77 RAB9A (0.65) KMT2AALDH1A1MAPTMEN1KDM4E
SCHEMBL7807341 0.74 NPC1 (0.58) KMT2AALDH1A1MAPTMEN1CYP1A2
SCHEMBL6141660 0.72 BCHE (0.83) KMT2AALDH1A1MAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996000224-A1 4-S- AND N-SUBSTITUTED 6-ALKYLPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1996-01-04 WO disclosed