SCHEMBL9053557

SCHEMBL9053557

Cc1cc(SCc2ccco2)cc(CSc2nc3ccccc3[nH]2)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
MAPT P10636 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
KDM4E B2RXH2 1/20 0.51
PKM P14618 1/20 0.51
NOS3 P29474 1/20 0.48
NOS1 P29475 1/20 0.48
NOS2 P35228 1/20 0.48
RAB9A P51151 8/20 0.48
NPC1 O15118 6/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
LMNA P02545 3/20 0.48
MAPK1 P28482 3/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP2E1 P05181 1/20 0.47
CYP2C8 P10632 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9054060 0.87 SMN1; SMN2 (0.39) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL9051302 0.86 NOS2 (0.48) ALDH1A1MAPTMEN1KMT2ANOS3
SCHEMBL8309586 0.85 NOS3 (0.58) ALDH1A1MAPTKDM4EPKMNOS3
Hydrochloric Acid SCHEMBL9053259 0.81 MAPT (0.38) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL9052207 0.79 KMT2A (0.53) ALDH1A1MAPTMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL9052566 0.78 KMT2A (0.52) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL9052994 0.76 MAPT (0.60) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL9052094 0.76 HSD17B10 (0.44) ALDH1A1MAPTKMT2AKDM4EPKM
SCHEMBL8008219 0.75 RAB9A (0.56) ALDH1A1MEN1KMT2ANOS3NOS1
Hydrochloric Acid SCHEMBL9051459 0.75 ALDH1A1 (0.44) ALDH1A1MAPTKMT2AKDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996000224-A1 4-S- AND N-SUBSTITUTED 6-ALKYLPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1996-01-04 WO disclosed