Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279904 | 0.83 | — | — | |
| SCHEMBL11201857 | 0.76 | TSHR (0.47) | TSHRALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL8458100 | 0.74 | NPC1 (0.51) | RAB9AALDH1A1NPC1HTTKMT2A | |
| SCHEMBL8830953 | 0.67 | ALDH1A1 (0.40) | TSHRRAB9AALDH1A1NPC1HTT | |
| SCHEMBL4177355 | 0.67 | TSHR (0.30) | TSHR | |
| SCHEMBL68171 | 0.67 | — | — | |
| SCHEMBL10908270 | 0.65 | RAB9A (0.32) | TSHRRAB9AALDH1A1NPC1HTT | |
| SCHEMBL9613797 | 0.65 | — | — | |
| SCHEMBL4446407 | 0.65 | — | — | |
| SCHEMBL1123477 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040107-A1 | THE USE OF N,N'-BIS(MERCAPTOACETYL) HYDRAZINE DRIVATIVES AS ANTICATARACT AGENTS | ALCON LABORATORIES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |