SCHEMBL2102653

SCHEMBL2102653

CCN(CC)[Si](C)(c1ccccc1)N(CC)CC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
TP53 P04637 1/20 0.35
TSHR P16473 2/20 0.34
ALDH1A1 P00352 1/20 0.34
GLA P06280 1/20 0.34
NR1I2 O75469 1/20 0.34
HTR1A P08908 2/20 0.33
MAPT P10636 2/20 0.33
ELANE P08246 1/20 0.33
CHRM2 P08172 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD1 P21728 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2100148 0.89 MAPT (0.34) ESR1ESR2TP53TSHRALDH1A1
SCHEMBL10626373 0.81 ESR1 (0.37) ESR1ESR2TP53TSHRALDH1A1
SCHEMBL2272577 0.81 ESR1 (0.37) ESR1ESR2TP53TSHRALDH1A1
SCHEMBL16033382 0.80 MEN1 (0.47) ESR1ESR2ALDH1A1NR1I2MAPT
SCHEMBL9052501 0.79 ESR1 (0.35) ESR1ESR2TP53TSHRALDH1A1
SCHEMBL2100019 0.78 TP53 (0.36) ESR1ESR2TP53TSHRALDH1A1
SCHEMBL2102622 0.78 KCNH2 (0.39) ESR1ESR2TP53TSHRALDH1A1
SCHEMBL2271289 0.78 TP53 (0.36) ESR1ESR2TP53TSHRALDH1A1
SCHEMBL9979418 0.78 TP53 (0.36) ESR1ESR2TP53TSHRALDH1A1
SCHEMBL2101600 0.77 NR1I2 (0.36) ESR1ESR2TP53TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384917-B1 Physical characteristics of polysilylether polymers in additive manufacturing of energetic materials THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2025-08-12 US disclosed
US-11661483-B1 Syntheses of polysilylether polymers in additive manufacturing of energetic materials THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-05-30 US disclosed
CN-104974184-B preparation of silazane Compounds 信越化学工业株式会社 2019-12-06 CN disclosed
EP-2930177-B1 PREPARATION OF SILAZANE COMPOUND SHINETSU CHEMICAL CO (JP) 2018-04-25 EP disclosed
US-9416147-B2 Preparation of silazane compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-16 US disclosed
EP-2930177-A1 Preparation of silazane compound Shin-Etsu Chemical Co., Ltd. (JP) 2015-10-14 EP disclosed
US-20150284414-A1 PREPARATION OF SILAZANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-10-08 US disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed
US-4448939-A SYNTHETIC RUBBERS; COATINGS; ADHESIVES AIR PRODUCTS AND CHEMICALS, INC. (US) 1984-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284414-A1 PREPARATION OF SILAZANE COMPOUND SLTM, SKP2, BCAT2 ESR1 4051/4885ESR2 4438/4885TP53 604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.