Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052425 | 0.87 | HPGD (0.47) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL9052117 | 0.83 | HPGD (0.48) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL8986025 | 0.79 | DRD2 (0.56) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL9052143 | 0.78 | OPRM1 (0.48) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL9052113 | 0.77 | HPGD (0.47) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL9051740 | 0.77 | HPGD (0.47) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL9053033 | 0.77 | OPRM1 (0.46) | SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL9052177 | 0.76 | SLC18A3 (0.49) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL9052441 | 0.76 | CA12 (0.44) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL9050709 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |