Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052425 | 0.90 | HPGD (0.47) | OPRM1OPRD1OPRK1OPRL1NR3C1 | |
| SCHEMBL2950781 | 0.87 | OPRM1 (0.50) | OPRM1OPRD1OPRK1OPRL1NR3C1 | |
| SCHEMBL9052524 | 0.85 | OPRM1 (0.50) | OPRM1OPRD1OPRK1OPRL1MAPT | |
| SCHEMBL2949377 | 0.81 | NR3C1 (0.43) | OPRM1OPRD1OPRK1OPRL1NR3C1 | |
| SCHEMBL22678127 | 0.77 | OPRL1 (0.49) | OPRM1OPRD1OPRK1OPRL1NR3C1 | |
| SCHEMBL27619102 | 0.77 | HTR2A (0.70) | MAPTL3MBTL1HTR2AHTR2CHTR2B | |
| SCHEMBL9052573 | 0.77 | HPGD (0.46) | MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL18987004 | 0.76 | GSK3B (0.49) | MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9052143 | 0.76 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1SMN1; SMN2 | |
| SCHEMBL9051892 | 0.75 | KDM4E (0.51) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |