Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053033 | 0.90 | OPRM1 (0.46) | SMN1; SMN2L3MBTL1AVPR1AGRIN2BNR3C1 | |
| SCHEMBL9052573 | 0.87 | HPGD (0.46) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL9052143 | 0.86 | OPRM1 (0.48) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL2950781 | 0.84 | OPRM1 (0.50) | HPGDSMN1; SMN2L3MBTL1AVPR1AGRIN2B | |
| SCHEMBL8986025 | 0.82 | DRD2 (0.56) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL9052202 | 0.80 | GRIN2B (0.50) | HPGDSMN1; SMN2L3MBTL1GRIN2BHTR1A | |
| SCHEMBL9052117 | 0.79 | HPGD (0.48) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL2949377 | 0.79 | NR3C1 (0.43) | SMN1; SMN2AVPR1AGRIN2BNR3C1OPRM1 | |
| SCHEMBL9051740 | 0.78 | HPGD (0.47) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 | |
| SCHEMBL9052113 | 0.78 | HPGD (0.47) | HPGDSMN1; SMN2L3MBTL1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |