Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21865146 | 0.85 | THRB (0.65) | THRBRECQLALDH1A1L3MBTL1LMNA | |
| SCHEMBL369480 | 0.78 | ALDH1A1 (0.62) | THRBRECQLALDH1A1L3MBTL1LMNA | |
| SCHEMBL1827781 | 0.78 | ALDH1A1 (0.53) | THRBRECQLALDH1A1L3MBTL1LMNA | |
| SCHEMBL569032 | 0.78 | ALDH1A1 (0.67) | THRBRECQLALDH1A1L3MBTL1LMNA | |
| SCHEMBL12545749 | 0.78 | RECQL (0.65) | THRBRECQLALDH1A1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL3492104 | 0.76 | ALDH1A1 (0.60) | THRBRECQLALDH1A1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL5009760 | 0.76 | ALDH1A1 (0.60) | THRBRECQLALDH1A1L3MBTL1LMNA | |
| SCHEMBL14505846 | 0.76 | RECQL (0.58) | THRBRECQLALDH1A1L3MBTL1LMNA | |
| SCHEMBL12016637 | 0.76 | RECQL (0.58) | THRBRECQLALDH1A1L3MBTL1LMNA | |
| SCHEMBL14845420 | 0.75 | THRB (0.53) | THRBRECQLALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690857-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDAL COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994013665-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDAL COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-06-23 | — | — | WO | disclosed |