Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31519040 | 0.82 | RAB9A (0.56) | ALDH1A1RECQLTHRBRAB9AHPGD | |
| SCHEMBL369480 | 0.81 | ALDH1A1 (0.62) | ALDH1A1RECQLTHRBRAB9AHPGD | |
| Hydrochloric Acid SCHEMBL3492104 | 0.79 | ALDH1A1 (0.60) | ALDH1A1RECQLTHRBRAB9AHPGD | |
| Hydrochloric Acid SCHEMBL5009760 | 0.79 | ALDH1A1 (0.60) | ALDH1A1RECQLTHRBRAB9AHPGD | |
| SCHEMBL9052767 | 0.78 | THRB (0.57) | ALDH1A1RECQLTHRBRAB9AHPGD | |
| Benzothiazyl Disulfide SCHEMBL28300456 | 0.78 | ALDH1A1 (0.79) | ALDH1A1RECQLRAB9AHPGDMAPT | |
| SCHEMBL9885425 | 0.78 | ALDH1A1 (0.50) | ALDH1A1RECQLTHRBRAB9AHPGD | |
| SCHEMBL14845420 | 0.78 | THRB (0.53) | ALDH1A1RECQLTHRBRAB9AHPGD | |
| Hydrochloric Acid SCHEMBL8687465 | 0.77 | NPC1 (0.58) | ALDH1A1RAB9AHPGDMAPTNPC1 | |
| SCHEMBL1757329 | 0.77 | ALDH1A1 (0.62) | ALDH1A1RECQLTHRBRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964954-B1 | N'-[(2-chlorobenzoyl)oxy]-1,3-benzothiazole-2-carboximidamide as an antitumor and antimicrobial compound | King Faisal University (SA) | 2024-04-23 | — | — | US | disclosed |
| US-11919892-B1 | 2-(benzo[d]thiazol-2-yl)-N'-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)acetimidamide as an antimicrobial compound | King Faisal University (SA) | 2024-03-05 | — | — | US | disclosed |
| US-7994225-B2 | Combination of an antibiotic and a drug such as pentamidine or salts thereof to treat drug resistant eye and ear infections | REMPEX PHARMACEUTICALS, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-7947741-B2 | Use and administration of bacterial efflux pump inhibitors | MPEX PHARMACEUTICALS, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| EP-1732527-A2 | USE AND ADMINISTRATION OF BACTERIAL EFFLUX PUMP INHIBITORS | MPEX PHARMACEUTICALS, INC. (US) | 2006-12-20 | — | — | EP | disclosed |
| US-20060276473-A1 | Use and administration of bacterial efflux pump inhibitors | REMPEX PHARMACEUTICALS, INC. | 2006-12-07 | — | — | US | disclosed |
| WO-2005089738-A2 | USE AND ADMINISTRATION OF BACTERIAL EFFLUX PUMP INHIBITORS | MPEX PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | WO | disclosed |
| EP-0058286-A1 | Geometrical isomers of cyano-guanidines, and processes for their preparation | Société de Recherches et de Synthèses Organiques SA (CH) | 1982-08-25 | — | — | EP | disclosed |
| US-4276421-A | Cyano-guanidine geometrical isomers | SOCIETE DE RECHERCHES ET DE SYNTHESES ORGANIQUES S.A. (CH) | 1981-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11919892-B1 | 2-(benzo[d]thiazol-2-yl)-N'-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)acetimidamide as an antimicrobial compound | AADAC, NIT2, B3GNT2 | ALDH1A1 605/4885RECQL 3969/4885THRB 3482/4885 |
| US-20060276473-A1 | Use and administration of bacterial efflux pump inhibitors | ABCB11, ABCC1, ABCB1 | ALDH1A1 2447/4885RECQL 247/4885THRB 3556/4885 |
| US-11964954-B1 | N'-[(2-chlorobenzoyl)oxy]-1,3-benzothiazole-2-carboximidamide as an antitumor and antimicrobial compound | CASP2, NCBP1, NOC2L | ALDH1A1 1515/4885RECQL 4377/4885THRB 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.