Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057834 | 0.82 | ALDH1A1 (0.59) | LMNATHRBALDH1A1KDM4EHPGD | |
| SCHEMBL9055484 | 0.82 | LMNA (0.47) | LMNATHRBALDH1A1TP53KDM4E | |
| SCHEMBL9058497 | 0.78 | LMNA (0.43) | LMNATHRBALDH1A1TP53KDM4E | |
| SCHEMBL4350914 | 0.76 | HDAC1 (0.51) | KDM4EMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2928098 | 0.75 | HPGD (0.49) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL9250823 | 0.74 | CDC25A (0.52) | LMNAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9257819 | 0.73 | NPC1 (0.50) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL3079120 | 0.73 | MAPT (0.50) | LMNATHRBALDH1A1TP53KDM4E | |
| SCHEMBL2925411 | 0.73 | CYP19A1 (0.56) | ALDH1A1KDM4EHPGDSMN1; SMN2NPC1 | |
| SCHEMBL22922181 | 0.72 | CYP4F2 (0.59) | LMNAALDH1A1HRH3MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |