Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | CDC25C | P30307 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EIF4E | P06730 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628694 | 0.83 | CYP11B1 (0.56) | CYP11B1CYP11B2ALDH1A1MAPTPOLB | |
| SCHEMBL9251061 | 0.82 | CYP11B1 (0.52) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3628690 | 0.81 | CYP11B1 (0.55) | CYP11B1CYP11B2ALDH1A1MAPTPOLB | |
| SCHEMBL1338556 | 0.81 | CYP11B1 (0.60) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9257819 | 0.81 | NPC1 (0.50) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9254684 | 0.80 | NPC1 (0.49) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19807125 | 0.80 | ATP4A (0.56) | RAB9AMAPTMAPK1MEN1KMT2A | |
| SCHEMBL22384228 | 0.80 | ATP4A (0.56) | RAB9AMAPTMAPK1MEN1KMT2A | |
| SCHEMBL9257792 | 0.79 | CYP11B1 (0.47) | CYP11B1CYP11B2KDM4EALDH1A1MAPT | |
| SCHEMBL9055484 | 0.78 | LMNA (0.47) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |