Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057834 | 0.84 | ALDH1A1 (0.59) | LMNATHRBKDM4EALDH1A1HPGD | |
| SCHEMBL9053099 | 0.82 | LMNA (0.43) | LMNATHRBTP53MAPTHRH3 | |
| SCHEMBL9058497 | 0.82 | LMNA (0.43) | LMNATHRBTP53MAPTHRH3 | |
| SCHEMBL9250823 | 0.78 | CDC25A (0.52) | LMNAMAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL9257819 | 0.77 | NPC1 (0.50) | AOC3MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3079120 | 0.77 | MAPT (0.50) | LMNATHRBTP53MAPTKDM4E | |
| SCHEMBL13680524 | 0.77 | MAPT (0.58) | LMNAPPARATP53MAPTKDM4E | |
| SCHEMBL22922181 | 0.76 | CYP4F2 (0.59) | LMNAMAPTHRH3ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9254684 | 0.76 | NPC1 (0.49) | AOC3MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL12087505 | 0.76 | HRH3 (0.51) | MAPTHRH3MAPK1MAPK10CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |