Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 15/20 | 0.36 |
| ▸ | MLYCD | O95822 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12948138 | 0.85 | MLYCD (0.42) | RIPK1MLYCD | |
| SCHEMBL9787049 | 0.82 | POLB (0.36) | MLYCDPOLB | |
| SCHEMBL9787050 | 0.80 | MLYCD (0.37) | MLYCD | |
| SCHEMBL14135048 | 0.79 | MAPT (0.44) | RIPK1MLYCD | |
| SCHEMBL6223670 | 0.79 | RIPK1 (0.50) | RIPK1LMNAPOLB | |
| SCHEMBL12948128 | 0.79 | PGR (0.39) | RIPK1MLYCD | |
| SCHEMBL7189485 | 0.79 | PGR (0.41) | MLYCD | |
| SCHEMBL5471636 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL14390414 | 0.78 | MLYCD (0.38) | RIPK1MLYCD | |
| SCHEMBL18792784 | 0.78 | HSD17B3 (0.48) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009046-A1 | 5α-REDUCTASE INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-03-28 | — | — | WO | disclosed |