Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.63 |
| ▸ | BCHE | P06276 | 3/20 | 0.63 |
| ▸ | ACHE | P22303 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062737 | 0.99 | MAOB (0.64) | MAOBBCHEACHE | |
| SCHEMBL6280891 | 0.87 | MAOB (0.75) | MAOBBCHEACHEALDH1A1ALDH2 | |
| SCHEMBL9053947 | 0.85 | MAOB (0.76) | MAOBBCHEACHEALDH1A1ALDH2 | |
| SCHEMBL9051412 | 0.85 | PARK7 (0.63) | MAOBBCHEACHE | |
| SCHEMBL9054162 | 0.81 | MAOB (0.57) | MAOBBCHEACHE | |
| SCHEMBL9050379 | 0.81 | MAOB (0.55) | MAOBBCHEACHEALDH1A1ALDH2 | |
| SCHEMBL4503347 | 0.81 | MAOB (0.56) | MAOBBCHEACHE | |
| SCHEMBL9049638 | 0.79 | MAOB (0.56) | MAOBBCHEACHE | |
| SCHEMBL15215070 | 0.79 | ALDH1A1 (0.70) | ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL21084263 | 0.74 | MAOB (1.00) | MAOBBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703901-A1 | 1-SUBSTITUTED ISATIN AND OXINDOLE DERIVATIVES AS INHIBITORS OF ACETYLCHOLINESTERASE | Astra Aktiebolag (SE) | 1996-04-03 | — | — | EP | claimed |
| WO-1994029272-A1 | 1-SUBSTITUTED ISATIN AND OXINDOLE DERIVATIVES AS INHIBITORS OF ACETYLCHOLINESTERASE | ASTRA AKTIEBOLAG (SE) | 1994-12-22 | — | — | WO | claimed |
| EP-0703901-A1 | 1-SUBSTITUTED ISATIN AND OXINDOLE DERIVATIVES AS INHIBITORS OF ACETYLCHOLINESTERASE | Astra Aktiebolag (SE) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029272-A1 | 1-SUBSTITUTED ISATIN AND OXINDOLE DERIVATIVES AS INHIBITORS OF ACETYLCHOLINESTERASE | ASTRA AKTIEBOLAG (SE) | 1994-12-22 | — | — | WO | disclosed |