Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053371 | 0.82 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1TDP1POLBRECQL | |
| SCHEMBL9053361 | 0.77 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TDP1POLBRECQL | |
| SCHEMBL9053452 | 0.77 | L3MBTL1 (0.48) | ALDH1A1L3MBTL1TDP1POLBRECQL | |
| SCHEMBL23754766 | 0.70 | LMNA (0.58) | ALDH1A1L3MBTL1TDP1GAAKDM4E | |
| SCHEMBL11656501 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNA | |
| SCHEMBL11656504 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNA | |
| SCHEMBL8773117 | 0.69 | TDP1 (0.57) | ALDH1A1L3MBTL1TDP1ESR2GAA | |
| SCHEMBL27636791 | 0.69 | PRSS1 (0.55) | L3MBTL1RECQLGAAKDM4EHPGD | |
| Trifluoroacetic Acid SCHEMBL11661114 | 0.68 | RECQL (0.37) | RECQL | |
| Trifluoroacetic Acid SCHEMBL11661111 | 0.68 | RECQL (0.37) | RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996007629-A1 | TECHNETIUM CHELATES TO BE USED FOR DETERMINING THE RENAL FUNCTION | MALLINCKRODT MEDICAL, INC. (US) | 1996-03-14 | — | — | WO | disclosed |