SCHEMBL9053371

SCHEMBL9053371

C[C@@H](N)C(=O)NCC(=O)NCC(=O)OC(=O)COC(=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
GAA P10253 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ADRB2 P07550 2/20 0.39
ADRB1 P08588 2/20 0.39
ADRB3 P13945 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
HPGD P15428 2/20 0.39
LMNA P02545 2/20 0.39
POLB P06746 1/20 0.39
RECQL P46063 1/20 0.39
ESR2 Q92731 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
TERT O14746 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9053457 0.82 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AL3MBTL1GAA
SCHEMBL9112878 0.77 CYP1A2 (0.54) ALDH1A1MEN1KMT2AL3MBTL1LMNA
SCHEMBL9053361 0.74 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AL3MBTL1GAA
SCHEMBL23754766 0.72 LMNA (0.58) ALDH1A1KMT2AL3MBTL1GAAKDM4E
SCHEMBL9053452 0.71 L3MBTL1 (0.48) ALDH1A1MEN1KMT2AL3MBTL1KDM4E
SCHEMBL8773117 0.70 TDP1 (0.57) ALDH1A1MEN1KMT2AL3MBTL1GAA
SCHEMBL27668472 0.70 LTA4H (0.45) ALDH1A1TERTNPC1RAB9A
Hydrochloric Acid SCHEMBL11683872 0.70 CYP1A2 (0.57) ALDH1A1MEN1KMT2AL3MBTL1LMNA
SCHEMBL2257751 0.69 TSHR (0.44) ALDH1A1MEN1KMT2ATDP1HPGD
SCHEMBL18515815 0.69 OPRM1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996007629-A1 TECHNETIUM CHELATES TO BE USED FOR DETERMINING THE RENAL FUNCTION MALLINCKRODT MEDICAL, INC. (US) 1996-03-14 WO disclosed