Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD2 | P25440 | 5/20 | 0.44 |
| ▸ | BRD4 | O60885 | 4/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29738286 | 0.75 | CES1 (0.35) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL4432600 | 0.75 | CES1 (0.35) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL20125004 | 0.73 | LMNA (0.38) | SMN1; SMN2LMNAMEN1KMT2ANPSR1 | |
| Iodide SCHEMBL27878012 | 0.73 | CES1 (0.34) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL2543813 | 0.70 | NPY5R (0.34) | BRD2BRD4BRD3SMN1; SMN2LMNA | |
| SCHEMBL29276950 | 0.70 | LMNA (0.33) | LMNANPSR1ALDH1A1MAPTUSP2 | |
| SCHEMBL1997095 | 0.70 | CACNA1G (0.43) | BRD2BRD4BRD3LMNASIGMAR1 | |
| Iodide SCHEMBL9515823 | 0.69 | NPY5R (0.33) | BRD2BRD4BRD3SMN1; SMN2LMNA | |
| Bromide SCHEMBL27894866 | 0.69 | NPY5R (0.33) | BRD2BRD4BRD3SMN1; SMN2LMNA | |
| SCHEMBL2538868 | 0.68 | LMNA (0.34) | LMNAMEN1KMT2ANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545535-A | USING MIXTURE OF FLUORESCENT DYES | MOLECULAR PROBES, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5436134-A | Fluorescent dyes for nucleic acids | MOLECULAR PROBES, INC. (US) | 1995-07-25 | — | — | US | disclosed |