Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432600 | 0.78 | CES1 (0.35) | LMNAMAPK1TSHRNPSR1USP2 | |
| SCHEMBL29738286 | 0.78 | CES1 (0.35) | LMNAMAPK1TSHRNPSR1USP2 | |
| Iodide SCHEMBL27878012 | 0.76 | CES1 (0.34) | LMNAMAPK1TSHRNPSR1USP2 | |
| SCHEMBL2193457 | 0.74 | NOTUM (0.57) | LMNANOTUMALDH1A1KDM4ECES1 | |
| SCHEMBL2538868 | 0.74 | LMNA (0.34) | LMNAMAPK1TSHRNPSR1USP2 | |
| SCHEMBL9053549 | 0.73 | BRD2 (0.44) | LMNAMAPK1TSHRNPSR1USP2 | |
| SCHEMBL29276950 | 0.73 | LMNA (0.33) | LMNAMAPK1TSHRNPSR1USP2 | |
| SCHEMBL2543813 | 0.73 | NPY5R (0.34) | LMNAMAPK1TSHRNPSR1USP2 | |
| Bromide SCHEMBL31147095 | 0.72 | S100A4 (0.34) | LMNAMAPK1TSHRNPSR1USP2 | |
| Iodide SCHEMBL27902564 | 0.72 | MAPT (0.34) | LMNAMAPK1TSHRNPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |