Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125004 | 0.74 | LMNA (0.38) | LMNAMAPK1USP2TSHRNPSR1 | |
| SCHEMBL29738286 | 0.72 | CES1 (0.35) | LMNAMAPK1USP2TSHRNPSR1 | |
| SCHEMBL4432600 | 0.72 | CES1 (0.35) | LMNAMAPK1USP2TSHRNPSR1 | |
| Iodide SCHEMBL27878012 | 0.71 | CES1 (0.34) | LMNAMAPK1USP2TSHRNPSR1 | |
| SCHEMBL2193457 | 0.69 | NOTUM (0.57) | LMNAALDH1A1NOTUMKDM4E | |
| SCHEMBL9053549 | 0.68 | BRD2 (0.44) | LMNAMAPK1USP2TSHRNPSR1 | |
| SCHEMBL2543813 | 0.68 | NPY5R (0.34) | LMNAMAPK1USP2TSHRNPSR1 | |
| SCHEMBL29276950 | 0.68 | LMNA (0.33) | LMNAMAPK1USP2TSHRNPSR1 | |
| Bromide SCHEMBL31147095 | 0.67 | S100A4 (0.34) | LMNAMAPK1USP2TSHRNPSR1 | |
| Iodide SCHEMBL27902564 | 0.67 | MAPT (0.34) | LMNAMAPK1USP2TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10029996-B2 | Class of cyano-substituted asymmetric cyanine dyes, synthesizing method and application thereof | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2018-07-24 | — | — | US | disclosed |
| US-20150118703-A1 | CLASS OF CYANO-SUBSTITUTED ASYMMETRIC CYANINE DYES, SYNTHESIZING METHOD AND APPLICATION THEREOF | SICHUAN ANKERUI NEW MATERIAL TECHNOLOGY CO., LTD (CN) | 2015-04-30 | — | — | US | disclosed |
| US-8298766-B2 | Fluorescent dyes, methods of synthesis and applications thereof | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2012-10-30 | — | — | US | disclosed |
| US-20110262904-A1 | FLUORESCENT DYES,METHODS OF SYNTHESIS AND APPLICATIONS THEREOF | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10029996-B2 | Class of cyano-substituted asymmetric cyanine dyes, synthesizing method and application thereof | HCCS, MKI67, MB | LMNA 299/4885IDO1 1305/4885MAPK1 3102/4885 |
| US-20150118703-A1 | CLASS OF CYANO-SUBSTITUTED ASYMMETRIC CYANINE DYES, SYNTHESIZING METHOD AND APPLICATION THEREOF | HCCS, MKI67, MB | LMNA 299/4885IDO1 1305/4885MAPK1 3102/4885 |
| US-20110262904-A1 | FLUORESCENT DYES,METHODS OF SYNTHESIS AND APPLICATIONS THEREOF | CBR3, CCR3, BCL3 | LMNA 230/4885IDO1 1648/4885MAPK1 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.