Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.43 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053405 | 0.88 | CYP3A4 (0.45) | RARARARBRARGALDH1A1TSHR | |
| SCHEMBL9053308 | 0.85 | RXRA (0.47) | RARARARBRARGALDH1A1KDM4E | |
| SCHEMBL9054413 | 0.80 | RARB (0.44) | RARARARBRARGALDH1A1HPGD | |
| SCHEMBL9054314 | 0.79 | RARB (0.46) | RARARARBRARGALDH1A1HPGD | |
| SCHEMBL9053667 | 0.78 | ALDH1A1 (0.52) | RARARARBRARGALDH1A1HPGD | |
| SCHEMBL3819796 | 0.74 | RARB (0.60) | RARARARBRARGRXRARXRG | |
| SCHEMBL9053306 | 0.69 | ALDH1A1 (0.47) | RARARARBRARGALDH1A1HPGD | |
| SCHEMBL9551786 | 0.69 | RARB (0.63) | RARARARBRARGRXRARXRG | |
| SCHEMBL9092406 | 0.69 | RARB (0.46) | RARARARBRARGALDH1A1KDM4E | |
| SCHEMBL1935437 | 0.69 | MAPT (0.55) | ALDH1A1HPGDKDM4ETSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996006070-A1 | DISUBSTITUTED ARYL AND HETEROARYL IMINES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1996-02-29 | — | — | WO | disclosed |