Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.63 |
| ▸ | ACHE | P22303 | 2/20 | 0.63 |
| ▸ | CYP2J2 | P51589 | 4/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915357 | 0.94 | BCHE (0.64) | BCHEACHE | |
| SCHEMBL9052298 | 0.94 | BCHE (0.64) | BCHEACHECYP2J2ADRA1DADRA1A | |
| SCHEMBL9051860 | 0.92 | DRD2 (0.67) | ADRA1ACYP3A4 | |
| SCHEMBL4509670 | 0.86 | CHRM1 (0.72) | BCHEACHECYP2J2ADRA1DADRA1A | |
| SCHEMBL9050713 | 0.86 | CCR3 (0.66) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9053162 | 0.85 | CCR3 (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7449796 | 0.84 | SIGMAR1 (0.74) | CYP3A4 | |
| SCHEMBL83059 | 0.84 | SIGMAR1 (0.69) | CYP3A4 | |
| SCHEMBL7401020 | 0.82 | SIGMAR1 (0.58) | CYP3A4 | |
| SCHEMBL7446629 | 0.82 | SIGMAR1 (0.72) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |