Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565400 | 0.77 | GPR119 (0.59) | HDAC4GPR119NPC1RAB9AHDAC6 | |
| SCHEMBL32676791 | 0.74 | EPHA2 (0.52) | HDAC4GPR119SMO | |
| SCHEMBL4415594 | 0.73 | HTT (0.57) | HDAC4GPR119 | |
| SCHEMBL4423384 | 0.73 | GPR119 (0.59) | HDAC4GPR119NPC1RAB9A | |
| SCHEMBL20116374 | 0.73 | SMO (0.51) | GPR119SMO | |
| SCHEMBL9059231 | 0.73 | MAPT (0.39) | NPC1RAB9AHDAC6 | |
| SCHEMBL12516250 | 0.73 | GPR119 (0.48) | HDAC4GPR119SMO | |
| SCHEMBL8560559 | 0.73 | NPC1 (0.40) | GPR119NPC1RAB9A | |
| SCHEMBL4419288 | 0.72 | LMNA (0.59) | HDAC4GPR119HDAC6 | |
| SCHEMBL12580564 | 0.72 | HDAC4 (0.56) | HDAC4GPR119HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |