Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051736 | 0.91 | TLR8 (0.51) | L3MBTL1POLBRAB9ACHEK1RET | |
| SCHEMBL10599732 | 0.89 | RAB9A (0.51) | L3MBTL1POLBRAB9ACHEK1RET | |
| SCHEMBL167579 | 0.87 | L3MBTL1 (0.53) | L3MBTL1POLBRAB9ACHEK1RET | |
| SCHEMBL4948626 | 0.78 | L3MBTL1 (0.58) | L3MBTL1POLBRAB9ACHEK1RET | |
| SCHEMBL27667676 | 0.76 | MAPT (0.43) | RAB9APIM1GSK3BLMNATP53 | |
| SCHEMBL14217911 | 0.75 | L3MBTL1 (0.47) | L3MBTL1POLBRAB9ACHEK1RET | |
| SCHEMBL7395253 | 0.74 | POLB (0.55) | L3MBTL1POLBRAB9ACHEK1RET | |
| SCHEMBL12282618 | 0.74 | MAPT (0.53) | L3MBTL1POLBRAB9ALMNATP53 | |
| SCHEMBL27667669 | 0.74 | CYP1A2 (0.41) | RAB9APIM1GSK3BCLK4TP53 | |
| SCHEMBL11886170 | 0.73 | ADORA3 (0.55) | L3MBTL1POLBRAB9ACHEK1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034591-A1 | DIAMINOPYRAZOLE-CONTAINING COMPOSITIONS FOR COLOURING KERATIN FIBRES, COLOURING PROCESS, NOVEL DIAMINOPYRAZOLES AND METHOD FOR THEIR PREPARATION | L'OREAL (FR) | 1996-11-07 | — | — | WO | claimed |