Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | YES1 | P07947 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055282 | 0.87 | MEN1 (0.44) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL8805377 | 0.78 | POLB (0.44) | ALDH1A1MEN1KMT2AHTTHSP90AA1 | |
| SCHEMBL8418190 | 0.75 | CYP19A1 (0.58) | ALDH1A1MEN1KMT2AHTTCYP3A4 | |
| SCHEMBL8806402 | 0.73 | TDP1 (0.42) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL8418131 | 0.72 | CYP19A1 (0.54) | ALDH1A1MEN1KMT2AHTTCYP3A4 | |
| SCHEMBL8415790 | 0.71 | HTR2C (0.67) | ALDH1A1MEN1KMT2AHTTCYP3A4 | |
| SCHEMBL9053943 | 0.70 | HTR6 (0.47) | ALDH1A1MEN1KMT2AHTTCYP3A4 | |
| SCHEMBL8418107 | 0.70 | CYP19A1 (0.56) | ALDH1A1MEN1KMT2AHTTCYP3A4 | |
| SCHEMBL9056449 | 0.69 | CYP19A1 (0.55) | ALDH1A1MEN1KMT2AHTTCYP3A4 | |
| SCHEMBL8806022 | 0.68 | CDK2 (0.49) | MEN1KMT2AMAPTNPSR1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |